5EK7

Structure of the autoinhibited Epha2 JMS-KD

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Ephrin type-A receptor 2	polymer	308	35071.4	2	UniProt (P29317) Pfam (PF14575) Pfam (PF07714)	Homo sapiens (Human)	Epithelial cell kinase,Tyrosine-protein kinase receptor ECK
2	C, D (A, B)	water	water		18.0	832	Chemie (HOH)

Sequence modifications

A, B: 583 - 876 (UniProt: P29317)

PDB	External Database	Details
Met 569	-	expression tag
Gly 570	-	expression tag
Ser 571	-	expression tag
Ser 572	-	expression tag
His 573	-	expression tag
His 574	-	expression tag
His 575	-	expression tag
His 576	-	expression tag
His 577	-	expression tag
His 578	-	expression tag
Ser 579	-	expression tag
Gln 580	-	expression tag
Asp 581	-	expression tag
Pro 582	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	70142.8
All*	Total formula weight	70142.8

*Water molecules are not included.