5EJM
ThDP-Mn2+ complex of R413A variant of EcMenD soaked with 2-ketoglutarate for 35 min
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | polymer | 556 | 61347.7 | 8 | UniProt (P17109) Pfam (PF02776) Pfam (PF16582) Pfam (PF02775) | Escherichia coli K12 | ThDP-dependent enzyme MenD,SEPHCHC synthase,Menaquinone biosynthesis protein MenD |
| 2 | CA, GA, I, KA, M... (F, G, A, H, B...) | (4~{R})-4-[3-[(4-azanyl-2-methyl-pyrimidin-5-yl)methyl]-4-methyl-5-[2-[oxidanyl(phosphonooxy)phosphoryl]oxyethyl]-1,3-thiazol-3-ium-2-yl]-4-oxidanyl-butanoic acid | non-polymer | 527.4 | 8 | Chemie (TD5) | |||
| 3 | DA, HA, J, LA, N... (F, G, A, H, B...) | MANGANESE (II) ION | non-polymer | 54.9 | 8 | Chemie (MN) | |||
| 4 | AA, EA, IA, K, MA... (E, F, G, A, H...) | GLYCEROL | non-polymer | 92.1 | 8 | Chemie (GOL) | |||
| 5 | BA, FA, JA, L, NA... (E, F, G, A, H...) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 8 | Chemie (EDO) | |||
| 6 | OA, PA, QA, RA, SA... (A, B, C, D, E...) | water | water | 18.0 | 4650 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H: 1 - 556 (UniProt: P17109)
| PDB | External Database | Details |
|---|---|---|
| Ala 413 | Arg 413 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 490781.3 | |
| Non-Polymers* | Number of molecules | 32 |
| Total formula weight | 5892.0 | |
| All* | Total formula weight | 496673.3 |
