5EIC
Crystal structure of the bromodomain of human CREBBP in complex with AYC
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | CREB-binding protein | polymer | 119 | 14223.3 | 2 | UniProt (Q92793) Pfam (PF00439) | Homo sapiens (Human) | |
| 2 | C, D (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 3 | E (B) | 2-[(chloroacetyl)amino]-5-[(E)-(4-sulfophenyl)diazenyl]benzenesulfonic acid | non-polymer | 433.8 | 1 | Chemie (5J5) | |||
| 4 | F, G (A, B) | water | water | 18.0 | 215 | Chemie (HOH) |
Sequence modifications
A, B: 1081 - 1197 (UniProt: Q92793)
| PDB | External Database | Details |
|---|---|---|
| Ser 1079 | - | expression tag |
| Met 1080 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 28446.7 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 558.0 | |
| All* | Total formula weight | 29004.7 |
