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5EG2

SET7/9 N265A in complex with AdoHcy and TAF10 peptide

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1AHistone-lysine N-methyltransferase SETD7polymer26229087.41UniProt (Q8WTS6)
Pfam (PF02493)
Pfam (PF00856)
In PDB
Homo sapiens (Human)Histone H3-K4 methyltransferase SETD7,H3-K4-HMTase SETD7,Lysine N-methyltransferase 7,SET domain-containing protein 7,SET7/9
2BTranscription initiation factor TFIID subunit 10polymer101242.41UniProt (Q12962)
In PDB
Homo sapiensSTAF28,Transcription initiation factor TFIID 30 kDa subunit,TAFII30
3AS-ADENOSYL-L-HOMOCYSTEINEnon-polymer384.41Chemie (SAH)
4ASODIUM IONnon-polymer23.01Chemie (NA)
5waterwater18.0316Chemie (HOH)
Sequence modifications
A: 110 - 366 (UniProt: Q8WTS6)
PDBExternal DatabaseDetails
Gly 105-expression tag
Ala 106-expression tag
Met 107-expression tag
Gly 108-expression tag
Ser 109-expression tag
Ala 265Asn 265engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight30329.8
Non-Polymers*Number of molecules2
Total formula weight407.4
All*Total formula weight30737.2
*Water molecules are not included.

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PDB entries from 2024-05-29

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