5EEG

Crystal structure of carminomycin-4-O-methyltransferase DnrK in complex with tetrazole-SAH

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Carminomycin 4-O-methyltransferase DnrK	polymer	376	41000.4	2	UniProt (Q06528) Pfam (PF00891)	Streptomyces peucetius	COMT,Anthracycline 4-O-methyltransferase
2	C, D (A, B)	(2~{R},3~{R},4~{S},5~{S})-2-(6-aminopurin-9-yl)-5-[[(3~{S})-3-azanyl-3-(1~{H}-1,2,3,4-tetrazol-5-yl)propyl]sulfanylmethyl]oxolane-3,4-diol	non-polymer		408.4	2	Chemie (S8M)
3	E, F (A, B)	water	water		18.0	490	Chemie (HOH)

Sequence modifications

A, B: 1 - 356 (UniProt: Q06528)

PDB	External Database	Details
Met -19	-	initiating methionine
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	82000.8
Non-Polymers*	Number of molecules	2
	Total formula weight	816.9
All*	Total formula weight	82817.7

*Water molecules are not included.