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5ED4

Structure of a PhoP-DNA complex

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, E, F
(A, B, E, F)
Response regulatorpolymer25027846.84UniProt (A0A045J469)
Pfam (PF00072)
Pfam (PF00486)
UniProt (by SIFTS) (P71814)
Mycobacterium tuberculosisPhoP family transcriptional regulator
2C, G
(C, G)
DNA (26-MER)polymer267931.12synthetic construct
3D, H
(D, H)
DNA (26-MER)polymer268042.22synthetic construct
4I, L, M, O, R...
(A, B, E, F)
CALCIUM IONnon-polymer40.16Chemie (CA)
5J, K, N, P
(A, B, E)
1,2-ETHANEDIOLnon-polymer62.14Chemie (EDO)
6Q
(E)
CACODYLATE IONnon-polymer137.01Chemie (CAC)
7AA, T, U, V, W...
(H, A, B, C, D...)
waterwater18.0233Chemie (HOH)
Sequence modifications
A, B, E, F: 1 - 247 (UniProt: A0A045J469)
PDBExternal DatabaseDetails
Gly -2-expression tag
Thr -1-expression tag
His 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains8
Total formula weight143333.8
Non-Polymers*Number of molecules11
Total formula weight625.7
All*Total formula weight143959.6
*Water molecules are not included.

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PDB entries from 2025-12-10

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