5ECG
Crystal structure of the BRCT domains of 53BP1 in complex with p53 and H2AX-pSer139 (gammaH2AX)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Cellular tumor antigen p53 | polymer | 225 | 25180.6 | 2 | UniProt (P04637) Pfam (PF00870) In PDB | Homo sapiens (Human) | Antigen NY-CO-13,Phosphoprotein p53,Tumor suppressor p53 |
2 | C, D | Tumor suppressor p53-binding protein 1 | polymer | 262 | 29624.5 | 2 | UniProt (Q12888) Pfam (PF18428) In PDB | Homo sapiens (Human) | p53BP1 |
3 | E, F | SEP-GLN-GLU-TYR | polymer | 4 | 605.5 | 2 | Homo sapiens | ||
4 | A, B | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
5 | water | water | 18.0 | 17 | Chemie (HOH) |
Sequence modifications
A, B: 95 - 312 (UniProt: P04637)
C, D: 1713 - 1972 (UniProt: Q12888)
PDB | External Database | Details |
---|---|---|
Gly 88 | - | expression tag |
Pro 89 | - | expression tag |
Leu 90 | - | expression tag |
Gly 91 | - | expression tag |
Ser 92 | - | expression tag |
His 93 | - | expression tag |
Met 94 | - | expression tag |
PDB | External Database | Details |
---|---|---|
His 1711 | - | expression tag |
Met 1712 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 110821.2 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 130.8 | |
All* | Total formula weight | 110952.1 |