5EC7
Crystal structure of a chimeric c-Src-SH3 domain with the sequence of the RT-loop from the Abl-SH3 domain at pH 5.0
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C | Proto-oncogene tyrosine-protein kinase Src | polymer | 57 | 6377.0 | 3 | UniProt (P00523) Pfam (PF00018) In PDB | Gallus gallus (Chicken) | Proto-oncogene c-Src,pp60c-src,p60-Src |
| 2 | A, B, C | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 4 | Chemie (PEG) | |||
| 3 | water | water | 18.0 | 102 | Chemie (HOH) |
Sequence modifications
A, B, C: 85 - 140 (UniProt: P00523)
| PDB | External Database | Details |
|---|---|---|
| Met 84 | - | initiating methionine |
| Val 93 | Glu 93 | engineered mutation |
| Ala 94 | Ser 94 | engineered mutation |
| Ser 95 | Arg 95 | engineered mutation |
| Gly 96 | Thr 96 | conflict |
| Arg 128 | Gln 128 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 19131.1 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 424.5 | |
| All* | Total formula weight | 19555.6 |
