5EAF

Saccharomyces cerevisiae CYP51 complexed with the plant pathogen inhibitor Fluquinconazole

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Lanosterol 14-alpha demethylase	polymer	539	61857.2	2	UniProt (A6ZSR0) Pfam (PF00067)	Saccharomyces cerevisiae (Baker's yeast)
2	C, E (A, B)	PROTOPORPHYRIN IX CONTAINING FE	non-polymer		616.5	2	Chemie (HEM)
3	D, F (A, B)	3-(2,4-dichlorophenyl)-6-fluoranyl-2-(1,2,4-triazol-1-yl)quinazolin-4-one	non-polymer		376.2	2	Chemie (FQC)
4	G, H (A, B)	water	water		18.0	36	Chemie (HOH)

Sequence modifications

A, B: 1 - 530 (UniProt: A6ZSR0)

PDB	External Database	Details
Ala 399	Val 399	conflict
Gly 531	-	expression tag
Gly 532	-	expression tag
Arg 533	-	expression tag
His 534	-	expression tag
His 535	-	expression tag
His 536	-	expression tag
His 537	-	expression tag
His 538	-	expression tag
His 539	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	123714.3
Non-Polymers*	Number of molecules	4
	Total formula weight	1985.3
All*	Total formula weight	125699.6

*Water molecules are not included.