5E8Q
Crystal structure of DHFR in 20% Isopropanol
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (B, A) | Dihydrofolate reductase | polymer | 159 | 18020.3 | 2 | UniProt (C3TR70) Pfam (PF00186) UniProt (by SIFTS) (P0ABQ4) | Escherichia coli | |
| 2 | C, I (B, A) | FOLIC ACID | non-polymer | 441.4 | 2 | Chemie (FOL) | |||
| 3 | D (B) | ISOPROPYL ALCOHOL | non-polymer | 60.1 | 1 | Chemie (IPA) | |||
| 4 | E (B) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 5 | F, G, H, J (B, A) | CHLORIDE ION | non-polymer | 35.5 | 4 | Chemie (CL) | |||
| 6 | K, L (B, A) | water | water | 18.0 | 324 | Chemie (HOH) |
Sequence modifications
B, A: 1 - 159 (UniProt: C3TR70)
| PDB | External Database | Details |
|---|---|---|
| Asp 37 | Asn 37 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 36040.7 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1124.8 | |
| All* | Total formula weight | 37165.4 |
