5E80
The crystal structure of PDEd in complex with inhibitor-2a
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | B, A | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | polymer | 149 | 17251.8 | 2 | UniProt (O43924) Pfam (PF05351) In PDB | Homo sapiens (Human) | GMP-PDE delta,Protein p17 |
2 | B, A | N-(3-chloro-2-methylphenyl)-4-(3,4-dimethyl-7-oxo-2-phenyl-2,7-dihydro-6H-pyrazolo[3,4-d]pyridazin-6-yl)butanamide | non-polymer | 449.9 | 2 | Chemie (5KP) | |||
3 | water | water | 18.0 | 15 | Chemie (HOH) |
Sequence modifications
B, A: 2 - 150 (UniProt: O43924)
PDB | External Database | Details |
---|---|---|
Ala 26 | Glu 26 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 34503.5 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 899.9 | |
All* | Total formula weight | 35403.4 |