5E6M

Crystal structure of human wild type GlyRS bound with tRNAGly

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Glycine--tRNA ligase	polymer	693	78704.8	2	UniProt (P41250) Pfam (PF00458) Pfam (PF00587) Pfam (PF03129)	Homo sapiens (Human)	Diadenosine tetraphosphate synthetase,AP-4-A synthetase,Glycyl-tRNA synthetase,GlyRS
2	C, D (C, E)	tRNA(Gly)	polymer	74	23900.0	2	GenBank (174921)	Homo sapiens
3	E, G (A, B)	GLYCYL-ADENOSINE-5'-PHOSPHATE	non-polymer		404.3	2	Chemie (GAP)
4	F (A)	SULFATE ION	non-polymer		96.1	1	Chemie (SO4)
5	H, I (C, E)	NICKEL (II) ION	non-polymer		58.7	2	Chemie (NI)
6	J, K, L, M (A, B, C, E)	water	water		18.0	72	Chemie (HOH)

Sequence modifications

A, B: 1 - 685 (UniProt: P41250)

PDB	External Database	Details
Leu 686	-	expression tag
Glu 687	-	expression tag
His 688	-	expression tag
His 689	-	expression tag
His 690	-	expression tag
His 691	-	expression tag
His 692	-	expression tag
His 693	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	205209.7
Non-Polymers*	Number of molecules	5
	Total formula weight	1022.0
All*	Total formula weight	206231.6

*Water molecules are not included.