5E6I

Crystal structure of TCR PF8 in complex with flu MP(58-66) epitope presented by HLA-A2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	G, A, F, P	TCR alpha chain,Human nkt tcr alpha chain	polymer	208	22716.1	4	UniProt (K7N5M3) Pfam (PF07686) Pfam (PF09291) In PDB	Homo sapiens	Human nkt tcr beta chain
2	H, B, L, Q	T-cell receptor beta-2 chain C region	polymer	243	27767.1	4	UniProt (A0A087WZ08) In PDB	Homo sapiens (Human)
3	I, C, M, R	HLA class I histocompatibility antigen, A-2 alpha chain	polymer	276	31985.4	4	UniProt (P01892) Pfam (PF00129) Pfam (PF07654) UniProt (by SIFTS) (P04439) In PDB	Homo sapiens (Human)	MHC class I antigen A*2
4	J, D, N, U	Beta-2-microglobulin	polymer	100	11879.4	4	UniProt (P61769) Pfam (PF07654) In PDB	Homo sapiens (Human)
5	K, E, O, T	Matrix protein 1	polymer	9	966.2	4	UniProt (E9P5U1) UniProt (by SIFTS) (P03485) In PDB	Influenza A virus

Sequence modifications

G, A, F, P: 0 - 112 (PDB: 5E6I)
G, A, F, P: 113 - 207 (UniProt: K7N5M3)
H, B, L, Q: 0 - 242 (UniProt: A0A087WZ08)

PDB	External Database	Details
Met 0	Leu 19	conflict
Glu 18	Lys 37	conflict
-	Ser 115	deletion
Ile 96	Thr 116	conflict
Tyr 97	Val 117	conflict
Pro 98	Leu 118	conflict
Gly 99	His 119	conflict
Glu 100	Ser 120	conflict
Leu 101	Gln 121	conflict
Phe 102	Tyr 122	conflict
Glu 105	Pro 125	conflict
Ser 107	Thr 127	conflict
Thr 110	Leu 130	conflict
Glu 122	Lys 142	conflict
Cys 169	Ser 189	conflict
Ala 187	Cys 207	conflict

I, C, M, R: 1 - 275 (UniProt: P01892)

PDB	External Database	Details
Met 0	-	initiating methionine

J, D, N, U: 1 - 99 (UniProt: P61769)

PDB	External Database	Details
Met 0	-	initiating methionine

Contents of the asymmetric unit

Polymers	Number of chains	20
	Total formula weight	381256.5
All*	Total formula weight	381256.5

*Water molecules are not included.