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5E6H

A Linked Jumonji Domain of the KDM5A Lysine Demethylase

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Lysine-specific demethylase 5Apolymer33037944.81UniProt (P29375)
Pfam (PF02375)
Pfam (PF02373)
Homo sapiens (Human)Histone demethylase JARID1A,Jumonji/ARID domain-containing protein 1A,Retinoblastoma-binding protein 2,RBBP-2,Histone demethylase JARID1A,Jumonji/ARID domain-containing protein 1A,Retinoblastoma-binding protein 2,RBBP-2
2B
(A)
MANGANESE (II) IONnon-polymer54.91Chemie (MN)
3C
(A)
2-OXOGLUTARIC ACIDnon-polymer146.11Chemie (AKG)
4D, E
(A)
GLYCEROLnon-polymer92.12Chemie (GOL)
5F
(A)
waterwater18.0100Chemie (HOH)
Sequence modifications
A: 1 - 347 (UniProt: P29375)
PDBExternal DatabaseDetails
His -1-expression tag
Asn 0-expression tag
A: 348 - 588 (UniProt: P29375)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight37944.8
Non-Polymers*Number of molecules4
Total formula weight385.2
All*Total formula weight38330.1
*Water molecules are not included.

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PDB entries from 2025-06-18

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