5E5W

Hemagglutinin-esterase-fusion mutant structure of influenza D virus

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C	Hemagglutinin-esterase	polymer	427	46457.0	2	UniProt (K9LG83) Pfam (PF03996) Pfam (PF02710) In PDB	Influenza D virus (D/swine/Oklahoma/1334/2011)
2	B, D	Hemagglutinin-esterase	polymer	157	16670.6	2	UniProt (K9LG83) Pfam (PF08720) Pfam (PF00509) In PDB	Influenza D virus (D/swine/Oklahoma/1334/2011)
3	E, F, I	alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		1073.0	3	In PDB GlyTouCan (G94106MV)
4	G, H, K, L	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	4	In PDB GlyTouCan (G42666HT)
5	J	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		586.5	1	In PDB GlyTouCan (G15407YE)
6	B, D	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)
7		water	water		18.0	544	Chemie (HOH)

Sequence modifications

A, C: 3 - 429 (UniProt: K9LG83)

PDB	External Database	Details
Ala 57	Ser 73	engineered mutation
Ala 356	Asp 372	engineered mutation
Ala 359	His 375	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	126255.2
Branched	Number of molecules	8
	Total formula weight	5503.0
Non-Polymers*	Number of molecules	2
	Total formula weight	442.4
All*	Total formula weight	132200.6

*Water molecules are not included.