5E5N

Ketosynthase from module 6 of the bacillaene synthase from Bacillus subtilis 168 (C167S mutant, crystal form 1)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Polyketide synthase PksL	polymer	617	69028.0	4	UniProt (Q05470) Pfam (PF00109) Pfam (PF02801) Pfam (PF22336)	Bacillus subtilis (strain 168)	PKS
2	E, F, G, H (A, B, C, D)	water	water		18.0	1358	Chemie (HOH)

Sequence modifications

A, B, C, D: -1 - 595 (UniProt: Q05470)

PDB	External Database	Details
Met -21	-	initiating methionine
Gly -20	-	expression tag
Ser -19	-	expression tag
Ser -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
Ser -11	-	expression tag
Ser -10	-	expression tag
Gly -9	-	expression tag
Leu -8	-	expression tag
Val -7	-	expression tag
Pro -6	-	expression tag
Arg -5	-	expression tag
Gly -4	-	expression tag
Ser -3	-	expression tag
Ser -2	-	expression tag
Ser 169	Cys 3040	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	276111.9
All*	Total formula weight	276111.9

*Water molecules are not included.