5E4K

Structure of ligand binding region of uPARAP at pH 7.4

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	C-type mannose receptor 2	polymer	492	55881.8	1	UniProt (Q9UBG0) Pfam (PF00040) Pfam (PF00059) In PDB	Homo sapiens (Human)	uPARAP
2	A	CALCIUM ION	non-polymer		40.1	2	Chemie (CA)
3	A	SODIUM ION	non-polymer		23.0	1	Chemie (NA)
4	A	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)
5	A	PENTAETHYLENE GLYCOL	non-polymer		238.3	1	Chemie (1PE)
6	A	3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL	non-polymer		398.5	1	Chemie (PE5)
7		water	water		18.0	26	Chemie (HOH)

Sequence modifications

A: 31 - 510 (UniProt: Q9UBG0)

PDB	External Database	Details
Arg 29	-	expression tag
Ser 30	-	expression tag
Ile 43	Val 43	variant
Thr 511	-	expression tag
Arg 512	-	expression tag
Thr 513	-	expression tag
Gly 514	-	expression tag
His 515	-	expression tag
His 516	-	expression tag
His 517	-	expression tag
His 518	-	expression tag
His 519	-	expression tag
His 520	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	55881.8
Non-Polymers*	Number of molecules	7
	Total formula weight	1182.3
All*	Total formula weight	57064.2

*Water molecules are not included.