5E30
Crystal structure of H5 hemagglutinin Q226L mutant from the influenza virus A/duck/Egypt/10185SS/2010 (H5N1) with LSTc
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | C, A, E | Hemagglutinin | polymer | 333 | 37701.6 | 3 | UniProt (G8IPF0) Pfam (PF00509) In PDB | Influenza A virus | HEMAGGLUTININ HA1 CHAIN |
2 | D, B, F | Hemagglutinin | polymer | 180 | 20822.0 | 3 | UniProt (G8IPF0) Pfam (PF00509) In PDB | Influenza A virus | HEMAGGLUTININ HA2 CHAIN |
3 | G | beta-L-fucopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)][alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 716.7 | 1 | In PDB GlyTouCan (G62810GW) | |||
4 | H, J, L | N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose | branched | 836.7 | 3 | In PDB GlyTouCan (G03509EL) | |||
5 | I, K | beta-L-fucopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 570.5 | 2 | In PDB GlyTouCan (G46874CY) | |||
6 | C, E | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
7 | water | water | 18.0 | 160 | Chemie (HOH) |
Sequence modifications
C, A, E: 11 - 333 (UniProt: G8IPF0)
D, B, F: 1 - 175 (UniProt: G8IPF0)
PDB | External Database | Details |
---|---|---|
Ala 7 | - | expression tag |
Asp 8 | - | expression tag |
Pro 9 | - | expression tag |
Gly 10 | - | expression tag |
Leu 226 | Gln 237 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Arg 176 | - | expression tag |
Leu 177 | - | expression tag |
Val 178 | - | expression tag |
Pro 179 | - | expression tag |
Arg 180 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 175570.9 | |
Branched | Number of molecules | 6 |
Total formula weight | 4368.0 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 442.4 | |
All* | Total formula weight | 180381.3 |