5DX0
Crystal structure of CARM1, sinefungin, and H3 peptide (R17)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Histone-arginine methyltransferase CARM1 | polymer | 349 | 39623.1 | 4 | UniProt (Q86X55) Pfam (PF06325) Pfam (PF22528) | Homo sapiens (Human) | Coactivator-associated arginine methyltransferase 1,Protein arginine N-methyltransferase 4 |
| 2 | E, F, G, H (F, G, H, I) | H3 peptide | polymer | 20 | 1909.3 | 4 | UniProt (P84243) | Homo sapiens | |
| 3 | I, L, N, Q (A, B, C, D) | SINEFUNGIN | non-polymer | 381.4 | 4 | Chemie (SFG) | |||
| 4 | J, O (A, C) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 5 | K, M, P, R (A, B, C, D) | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 6 | S, T, U, V, W... (A, B, C, D, F...) | water | water | 18.0 | 458 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 134 - 479 (UniProt: Q86X55)
F, G, H, I: 1 - 18 (UniProt: P84243)
| PDB | External Database | Details |
|---|---|---|
| Ser 131 | - | expression tag |
| Ile 132 | - | expression tag |
| Ala 133 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ace 0 | - | acetylation |
| Nh2 19 | - | amidation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 166129.7 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 2094.0 | |
| All* | Total formula weight | 168223.7 |
