5DWZ
Structural and functional characterization of PqsBC, a condensing enzyme in the biosynthesis of the Pseudomonas aeruginosa quinolone signal
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | C, D, F, H | 3-oxoacyl-[acyl-carrier-protein] synthase 3 | polymer | 350 | 38327.5 | 4 | UniProt (A0A0C6EZ24) Pfam (PF08545) Pfam (PF08541) UniProt (by SIFTS) (Q9I4X1) In PDB | Pseudomonas aeruginosa | Beta-keto-ACP synthase,Beta-keto-acyl-acyl-carrier-like protein synthase,PQS biosynthesis protein PqsC,Uncharacterized protein |
2 | B, A, E, G | 3-oxoacyl-(Acyl carrier protein) synthase III | polymer | 283 | 30531.8 | 4 | UniProt (A0A072ZZD2) UniProt (by SIFTS) (Q9I4X2) In PDB | Pseudomonas aeruginosa | Beta-keto-ACP synthase,Beta-keto-acyl-acyl-carrier-like protein synthase,PQS biosynthesis protein PqsB,PqsB |
3 | A, F, C, E, H... | PHOSPHATE ION | non-polymer | 95.0 | 20 | Chemie (PO4) | |||
4 | D, C, B | GLYCEROL | non-polymer | 92.1 | 7 | Chemie (GOL) | |||
5 | D, C, H | 3[N-MORPHOLINO]PROPANE SULFONIC ACID | non-polymer | 209.3 | 4 | Chemie (MPO) | |||
6 | C | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 122.1 | 1 | Chemie (TRS) | |||
7 | D, C | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
8 | B | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 1 | Chemie (PGE) | |||
9 | D, H | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 3 | Chemie (PEG) | |||
10 | E | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
11 | water | water | 18.0 | 1095 | Chemie (HOH) |
Sequence modifications
C, D, F, H: 2 - 348 (UniProt: A0A0C6EZ24)
PDB | External Database | Details |
---|---|---|
Ser -1 | - | expression tag |
Ala 0 | - | expression tag |
Gly 1 | - | expression tag |
Ala 129 | Cys 129 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 8 |
Total formula weight | 275437.2 | |
Non-Polymers* | Number of molecules | 39 |
Total formula weight | 4065.7 | |
All* | Total formula weight | 279502.9 |