5DRB
Crystal structure of WNK1 in complex with WNK463
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Serine/threonine-protein kinase WNK1 | polymer | 291 | 33538.6 | 1 | UniProt (Q9JIH7) Pfam (PF00069) | Rattus norvegicus (Rat) | Protein kinase lysine-deficient 1, Protein kinase with no lysine 1 |
| 2 | B (A) | N-tert-butyl-1-(1-{5-[5-(trifluoromethyl)-1,3,4-oxadiazol-2-yl]pyridin-2-yl}piperidin-4-yl)-1H-imidazole-5-carboxamide | non-polymer | 463.5 | 1 | Chemie (5FJ) | |||
| 3 | C (A) | water | water | 18.0 | 254 | Chemie (HOH) |
Sequence modifications
A: 194 - 483 (UniProt: Q9JIH7)
| PDB | External Database | Details |
|---|---|---|
| Gly 193 | - | cloning artifact |
| Ala 382 | Ser 382 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 33538.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 463.5 | |
| All* | Total formula weight | 34002.0 |
