5DR2

Aurora A Kinase in Complex with AA30 and ATP in Space Group P6122

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Aurora kinase A	polymer	273	31807.5	1	UniProt (O14965) Pfam (PF00069) In PDB	Homo sapiens (Human)	Aurora 2,Aurora/IPL1-related kinase 1,hARK1,Breast tumor-amplified kinase,Serine/threonine-protein kinase 15,Serine/threonine-protein kinase 6,Serine/threonine-protein kinase aurora-A
2	A	2-(3-bromophenyl)quinoline-4-carboxylic acid	non-polymer		328.2	1	Chemie (5E1)
3	A	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)
4	A	ADENOSINE-5'-TRIPHOSPHATE	non-polymer		507.2	1	Chemie (ATP)
5		water	water		18.0	9	Chemie (HOH)

Sequence modifications

A: 128 - 390 (UniProt: O14965)

PDB	External Database	Details
Met 124	-	initiating methionine
Gly 125	-	expression tag
Arg 126	-	expression tag
Gln 127	-	expression tag
Ala 287	Thr 287	engineered mutation
His 391	-	expression tag
His 392	-	expression tag
His 393	-	expression tag
His 394	-	expression tag
His 395	-	expression tag
His 396	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	31807.5
Non-Polymers*	Number of molecules	3
	Total formula weight	859.6
All*	Total formula weight	32667.2

*Water molecules are not included.