5DQO
Crystal structure of Y347F mutant of human primase p58 iron-sulfur cluster domain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | DNA primase large subunit | polymer | 197 | 22655.9 | 4 | UniProt (P49643) Pfam (PF04104) | Homo sapiens (Human) | DNA primase 58 kDa subunit, p58 |
| 2 | E, F, G, H (A, B, C, D) | IRON/SULFUR CLUSTER | non-polymer | 351.6 | 4 | Chemie (SF4) | |||
| 3 | I, J, K, L (A, B, C, D) | water | water | 18.0 | 14 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 272 - 464 (UniProt: P49643)
| PDB | External Database | Details |
|---|---|---|
| Gly 268 | - | expression tag |
| Ser 269 | - | expression tag |
| Pro 270 | - | expression tag |
| Asn 271 | - | expression tag |
| Phe 347 | Tyr 347 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 90623.8 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1406.6 | |
| All* | Total formula weight | 92030.4 |
