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5DQ0

Structure of human neuropilin-2 b1 domain with novel and unique zinc binding site

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Neuropilin-2polymer16218368.61UniProt (O60462)
Pfam (PF00754)
Homo sapiens (Human)Vascular endothelial cell growth factor 165 receptor 2
2B, C, D
(A)
ZINC IONnon-polymer65.43Chemie (ZN)
3E, F
(A)
CHLORIDE IONnon-polymer35.52Chemie (CL)
4G, H
(A)
1,2-ETHANEDIOLnon-polymer62.12Chemie (EDO)
5I
(A)
2-(N-MORPHOLINO)-ETHANESULFONIC ACIDnon-polymer195.21Chemie (MES)
6J
(A)
waterwater18.0138Chemie (HOH)
Sequence modifications
A: 275 - 430 (UniProt: O60462)
PDBExternal DatabaseDetails
Gly 272-expression tag
His 273-expression tag
Met 274-expression tag
Ser 431-expression tag
Gly 432-expression tag
Ser 433-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight18368.6
Non-Polymers*Number of molecules8
Total formula weight586.5
All*Total formula weight18955.1
*Water molecules are not included.

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PDB entries from 2025-12-03

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