5DP7

Crystal Structure of EV71 3C Proteinase in complex with compound 5

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	3C proteinase	polymer	192	21391.5	1	UniProt (A9XG43) Pfam (PF00548) In PDB	Enterovirus A71
2	A	ethyl (2Z,4S)-4-{[N-(3-methylbutanoyl)-L-phenylalanyl]amino}-5-[(3S)-2-oxopyrrolidin-3-yl]pent-2-enoate	non-polymer		457.6	1	Chemie (5EC)
3		water	water		18.0	81	Chemie (HOH)

Sequence modifications

A: 1 - 183 (UniProt: A9XG43)

PDB	External Database	Details
Met 0	-	initiating methionine
Leu 184	-	expression tag
Glu 185	-	expression tag
His 186	-	expression tag
His 187	-	expression tag
His 188	-	expression tag
His 189	-	expression tag
His 190	-	expression tag
His 191	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	21391.5
Non-Polymers*	Number of molecules	1
	Total formula weight	457.6
All*	Total formula weight	21849.0

*Water molecules are not included.