5DP4
Crystal Structure of EV71 3C Proteinase in complex with compound 3
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | 3C proteinase | polymer | 192 | 21391.5 | 4 | UniProt (A9XG43) Pfam (PF00548) | Enterovirus A71 | |
| 2 | E, F, G, H (A, B, C, D) | ethyl (2Z,4S)-4-{[(2S)-2-methyl-3-phenylpropanoyl]amino}-5-[(3S)-2-oxopyrrolidin-3-yl]pent-2-enoate | non-polymer | 372.5 | 4 | Chemie (5E8) | |||
| 3 | I, J, K, L (A, B, C, D) | water | water | 18.0 | 363 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 183 (UniProt: A9XG43)
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | expression tag |
| Leu 184 | - | expression tag |
| Glu 185 | - | expression tag |
| His 186 | - | expression tag |
| His 187 | - | expression tag |
| His 188 | - | expression tag |
| His 189 | - | expression tag |
| His 190 | - | expression tag |
| His 191 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 85565.9 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1489.8 | |
| All* | Total formula weight | 87055.8 |
