5DOH

Crystal structure of human carbonic anhydrase isozyme II with 2-[(1S)-2,3-Dihydro-1H-inden-1-ylamino]-3,5,6-trifluoro-4-[(2-hydroxyethyl)thio]benzenesulfonamide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Carbonic anhydrase 2	polymer	260	29289.1	2	UniProt (P00918) Pfam (PF00194) In PDB	Homo sapiens (Human)	Carbonate dehydratase II,Carbonic anhydrase C,CAC,Carbonic anhydrase II,CA-II
2	A, B	ZINC ION	non-polymer		65.4	2	Chemie (ZN)
3	A, B	BICINE	non-polymer		163.2	2	Chemie (BCN)
4	A, B	DIMETHYL SULFOXIDE	non-polymer		78.1	2	Chemie (DMS)
5	A, B	2-[(1S)-2,3-dihydro-1H-inden-1-ylamino]-3,5,6-trifluoro-4-[(2-hydroxyethyl)sulfanyl]benzenesulfonamide	non-polymer		418.5	2	Chemie (5DU)
6		water	water		18.0	538	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	58578.1
Non-Polymers*	Number of molecules	8
	Total formula weight	1450.3
All*	Total formula weight	60028.5

*Water molecules are not included.