5DOB

Crystal structure of the Human Cytomegalovirus Nuclear Egress Complex (NEC)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Virion egress protein UL31 homolog	polymer	237	27176.2	1	UniProt (P16794) Pfam (PF02718) In PDB	Human cytomegalovirus (HHV-5)
2	B	Virion egress protein UL34 homolog	polymer	165	18452.3	1	UniProt (P16791) Pfam (PF04541) In PDB	Human cytomegalovirus (strain AD169) (HHV-5)	Primary envelopment factor UL34 homolog
3	A	ZINC ION	non-polymer		65.4	1	Chemie (ZN)
4	A	CALCIUM ION	non-polymer		40.1	1	Chemie (CA)

Sequence modifications

A: 61 - 289 (UniProt: P16794)

PDB	External Database	Details
Gly 53	-	expression tag
Pro 54	-	expression tag
Leu 55	-	expression tag
Gly 56	-	expression tag
Ser 57	-	expression tag
Met 58	-	expression tag
Leu 59	-	expression tag
Lys 60	-	expression tag
Ser 62	His 62	engineered mutation
Glu 63	Asp 63	engineered mutation
Val 67	Ile 67	engineered mutation
Gln 69	Arg 69	engineered mutation
Arg 70	Glu 70	engineered mutation

B: 4 - 168 (UniProt: P16791)

PDB	External Database	Details
Ala 66	Thr 66	conflict
Ala 92	Lys 92	conflict

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	45628.6
Non-Polymers*	Number of molecules	2
	Total formula weight	105.5
All*	Total formula weight	45734.1

*Water molecules are not included.