5DKC
Crystal structure of the bromodomain of human BRM (SMARCA2) in complex with PFI-3 chemical probe
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Probable global transcription activator SNF2L2 | polymer | 123 | 14380.5 | 1 | UniProt (P51531) Pfam (PF00439) In PDB | Homo sapiens (Human) | ATP-dependent helicase SMARCA2,BRG1-associated factor 190B,BAF190B,Protein brahma homolog,hBRM,SNF2-alpha,SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 |
| 2 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 3 | A | (2E)-1-(2-hydroxyphenyl)-3-[(1R,4R)-5-(pyridin-2-yl)-2,5-diazabicyclo[2.2.1]hept-2-yl]prop-2-en-1-one | non-polymer | 321.4 | 1 | Chemie (5BW) | |||
| 4 | water | water | 18.0 | 114 | Chemie (HOH) |
Sequence modifications
A: 1373 - 1493 (UniProt: P51531)
| PDB | External Database | Details |
|---|---|---|
| Ser 1371 | - | expression tag |
| Met 1372 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 14380.5 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 386.8 | |
| All* | Total formula weight | 14767.3 |
