5DJV
Crystal structure of human FPPS in complex with biaryl compound 8e
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | F | Farnesyl pyrophosphate synthase | polymer | 350 | 40183.9 | 1 | UniProt (P14324) Pfam (PF00348) In PDB | Homo sapiens (Human) | FPS,(2E,6E)-farnesyl diphosphate synthase,Dimethylallyltranstransferase,Farnesyl diphosphate synthase,Geranyltranstransferase |
2 | F | 8-(naphthalen-1-yl)-6-(1H-pyrrol-2-yl)quinoline-2-carboxylic acid | non-polymer | 364.4 | 1 | Chemie (5BL) | |||
3 | water | water | 18.0 | 27 | Chemie (HOH) |
Sequence modifications
F: 6 - 353 (UniProt: P14324)
PDB | External Database | Details |
---|---|---|
Gly 4 | - | expression tag |
Pro 5 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 40183.9 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 364.4 | |
All* | Total formula weight | 40548.3 |