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5DFH

Human APE1 mismatch product complex

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
DNA-(apurinic or apyrimidinic site) lyasepolymer27631188.52UniProt (P27695)
Pfam (PF03372)
Homo sapiens (Human)APEX nuclease,APEN,Apurinic-apyrimidinic endonuclease 1,APE-1,REF-1,Redox factor-1
2C
(D)
DNA (5'-D(P*(3DR)P*CP*GP*AP*CP*GP*GP*AP*TP*CP*C)-3')polymer113210.11synthetic construct
3D
(V)
DNA (5'-D(*GP*GP*AP*TP*CP*CP*GP*TP*CP*GP*GP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3')polymer216465.21synthetic construct
4E
(C)
DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*T)-3')polymer103076.01synthetic construct
5F
(A)
1,2-ETHANEDIOLnon-polymer62.11Chemie (EDO)
6G
(A)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
7H, I, J, K, L
(A, B, D, V, C)
waterwater18.0377Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains5
Total formula weight75128.3
Non-Polymers*Number of molecules2
Total formula weight86.4
All*Total formula weight75214.7
*Water molecules are not included.

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PDB entries from 2024-11-06

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