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5DFF

Human APE1 product complex

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
DNA-(apurinic or apyrimidinic site) lyasepolymer27631188.52UniProt (P27695)
Pfam (PF03372)
Homo sapiens (Human)APEX nuclease,APEN,Apurinic-apyrimidinic endonuclease 1,APE-1,REF-1,Redox factor-1
2C
(D)
DNA (5'-D(P*(3DR)P*CP*GP*AP*CP*GP*GP*AP*TP*CP*C)-3')polymer113210.11synthetic construct
3D
(P)
DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*C)-3')polymer103061.01synthetic construct
4E
(V)
DNA (5'-D(*GP*GP*AP*TP*CP*CP*GP*TP*CP*GP*GP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3')polymer216465.21synthetic construct
5F
(A)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
6G, K
(A, B)
DI(HYDROXYETHYL)ETHERnon-polymer106.12Chemie (PEG)
7H
(A)
CHLORIDE IONnon-polymer35.51Chemie (CL)
8I, J, L, M
(A, B)
1,2-ETHANEDIOLnon-polymer62.14Chemie (EDO)
9N, O, P, Q, R
(A, B, D, P, V)
waterwater18.0684Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains5
Total formula weight75113.3
Non-Polymers*Number of molecules8
Total formula weight520.3
All*Total formula weight75633.6
*Water molecules are not included.

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PDB entries from 2025-10-15

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