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5DE8

Crystal structure of the complex between human FMRP RGG motif and G-quadruplex RNA, iridium hexammine bound form.

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, C
(A, C)
sc1polymer3511459.82synthetic construct
2B, D
(B, D)
Fragile X mental retardation protein 1polymer181788.92UniProt (Q06787)Homo sapiensProtein FMR-1
3E, I
(A, C)
POTASSIUM IONnon-polymer39.12Chemie (K)
4F, G, H, J, K
(A, C)
IRIDIUM HEXAMMINE IONnon-polymer294.45Chemie (IRI)
Sequence modifications
B, D: 3 - 20 (UniProt: Q06787)
PDBExternal DatabaseDetails
Ala 3Arg 527conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight26497.5
Non-Polymers*Number of molecules7
Total formula weight1550.2
All*Total formula weight28047.7
*Water molecules are not included.

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PDB entries from 2025-06-18

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