5DBM
Crystal structure of the CBP bromodomain in complex with CPI703
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | CREB-binding protein | polymer | 118 | 13992.0 | 3 | UniProt (Q92793) Pfam (PF00439) | Homo sapiens (Human) | |
| 2 | D, E, F (A, B, C) | (4R)-6-(1-tert-butyl-1H-pyrazol-4-yl)-4-methyl-1,3,4,5-tetrahydro-2H-1,5-benzodiazepin-2-one | non-polymer | 298.4 | 3 | Chemie (58N) | |||
| 3 | G, H, I (A, B, C) | water | water | 18.0 | 355 | Chemie (HOH) |
Sequence modifications
A, B, C: 1082 - 1197 (UniProt: Q92793)
| PDB | External Database | Details |
|---|---|---|
| Gly 1080 | - | expression tag |
| Ser 1081 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 41976.0 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 895.1 | |
| All* | Total formula weight | 42871.2 |
