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5D9Y

Crystal structure of TET2-5fC complex

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Methylcytosine dioxygenase TET2,Methylcytosine dioxygenase TET2polymer46251397.41UniProt (Q6N021)
Pfam (PF12851)
Homo sapiens (Human)
2B
(B)
DNA (5'-D(*AP*CP*TP*GP*TP*(5FC)P*GP*AP*AP*GP*CP*T)-3')polymer123690.41synthetic construct
3C
(C)
DNA (5'-D(*AP*GP*CP*TP*TP*CP*GP*AP*CP*AP*GP*T)-3')polymer123662.41synthetic construct
4D
(A)
N-OXALYLGLYCINEnon-polymer147.11Chemie (OGA)
5E
(A)
FE (III) IONnon-polymer55.81Chemie (FE)
6F, G, H
(A)
ZINC IONnon-polymer65.43Chemie (ZN)
7I, J, K
(A, B, C)
waterwater18.0262Chemie (HOH)
Sequence modifications
A: 1129 - 1828 (UniProt: Q6N021)
PDBExternal DatabaseDetails
Gly 1127-expression tag
Ser 1128-expression tag
A: 1844 - 1936 (UniProt: Q6N021)
PDBExternal DatabaseDetails
Gly 1829-linker
Gly 1830-linker
Gly 1831-linker
Gly 1832-linker
Ser 1833-linker
Gly 1834-linker
Gly 1835-linker
Gly 1836-linker
Gly 1837-linker
Ser 1838-linker
Gly 1839-linker
Gly 1840-linker
Gly 1841-linker
Gly 1842-linker
Ser 1843-linker
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight58750.2
Non-Polymers*Number of molecules5
Total formula weight399.2
All*Total formula weight59149.3
*Water molecules are not included.

239149

PDB entries from 2025-07-23

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