5D8J
Development of a therapeutic monoclonal antibody targeting secreted aP2 to treat type 2 diabetes.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Fatty acid-binding protein, adipocyte | polymer | 134 | 14815.0 | 1 | UniProt (P04117) Pfam (PF00061) | Mus musculus (House Mouse) | 3T3-L1 lipid-binding protein,Adipocyte lipid-binding protein,ALBP,Adipocyte-type fatty acid-binding protein,AFABP,Fatty acid-binding protein 4,Myelin P2 protein homolog,P15,P2 adipocyte protein,Protein 422 |
| 2 | B (H) | HA3 Fab Heavy Chain | polymer | 221 | 23733.5 | 1 | Mus musculus (House Mouse) | ||
| 3 | C (L) | HA3 Fab Light Chain | polymer | 215 | 23515.9 | 1 | Mus musculus (House Mouse) | ||
| 4 | D (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 5 | E, F, G (A, H, L) | water | water | 18.0 | 13 | Chemie (HOH) |
Sequence modifications
A: 1 - 132 (UniProt: P04117)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 62064.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 96.1 | |
| All* | Total formula weight | 62160.4 |
