5D7Y
Crystal structure of Hepatitis B virus T=4 capsid in complex with the allosteric modulator HAP18
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | Capsid protein | polymer | 150 | 16823.2 | 4 | UniProt (P03147) Pfam (PF00906) In PDB | Hepatitis B virus genotype D subtype adw (isolate United Kingdom/adyw/1979) (HBV-D) | Core antigen, Core protein, HBcAg, p21.5 |
| 2 | B, C | methyl (4R)-4-(2-chloro-4-fluorophenyl)-6-{[4-(3-hydroxypenta-1,4-diyn-3-yl)piperidin-1-yl]methyl}-2-(pyridin-2-yl)-1,4-dihydropyrimidine-5-carboxylate | non-polymer | 521.0 | 2 | Chemie (58H) |
Sequence modifications
A, B, C, D: 1 - 149 (UniProt: P03147)
| PDB | External Database | Details |
|---|---|---|
| Ala 48 | Cys 48 | engineered mutation |
| Ala 61 | Cys 61 | engineered mutation |
| Met 93 | Val 93 | engineered mutation |
| Ala 107 | Cys 107 | engineered mutation |
| Cys 150 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 67292.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1042.0 | |
| All* | Total formula weight | 68334.6 |
