5D70
Crystal structure of MOR03929, a neutralizing anti-human GM-CSF antibody Fab fragment in complex with human GM-CSF
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Granulocyte-macrophage colony-stimulating factor | polymer | 127 | 14492.5 | 1 | UniProt (P04141) Pfam (PF01109) | Homo sapiens (Human) | GM-CSF,Colony-stimulating factor,CSF,Molgramostin,Sargramostim |
| 2 | B (H) | Immunglobulin G1 Fab fragment, heavy chain | polymer | 236 | 25321.0 | 1 | Homo sapiens (Human) | ||
| 3 | C (L) | Immunglobulin G1 Fab fragment, light chain | polymer | 209 | 22229.6 | 1 | Homo sapiens (Human) | ||
| 4 | D (L) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 5 | E, F, G (A, H, L) | water | water | 18.0 | 330 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 62043.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 96.1 | |
| All* | Total formula weight | 62139.2 |
