5D5A
In meso in situ serial X-ray crystallography structure of the Beta2-adrenergic receptor at 100 K
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Beta-2 adrenergic receptor,Endolysin,Beta-2 adrenergic receptor | polymer | 500 | 56601.4 | 1 | UniProt (P07550) UniProt (P00720) Pfam (PF00001) Pfam (PF00959) | Homo sapiens (Human) | Beta-2 adrenoreceptor,Beta-2 adrenoceptor,Lysis protein,Lysozyme,Muramidase,Beta-2 adrenoreceptor,Beta-2 adrenoceptor |
| 2 | B (B) | alpha-D-glucopyranose-(1-4)-beta-D-glucopyranose | branched | 342.3 | 1 | In PDB BIRD (PRD_900018) GlyTouCan (G66120GK) | beta-maltose | ||
| 3 | C (A) | (2S)-1-(9H-Carbazol-4-yloxy)-3-(isopropylamino)propan-2-ol | non-polymer | 298.4 | 1 | Chemie (CAU) | |||
| 4 | D, E (A) | 1,4-BUTANEDIOL | non-polymer | 90.1 | 2 | Chemie (BU1) PubChem (8064) | |||
| 5 | F (A) | ACETAMIDE | non-polymer | 59.1 | 1 | Chemie (ACM) | |||
| 6 | G, H, I (A) | CHOLESTEROL | non-polymer | 386.7 | 3 | Chemie (CLR) PubChem (16219173) PubChem (16758052) PubChem (176980071) PubChem (18640088) PubChem (1715243) PubChem (1715244) PubChem (23423981) PubChem (44654663) PubChem (46937002) PubChem (40477506) PubChem (40557614) PubChem (42579431) PubChem (42579432) PubChem (59274407) PubChem (45044259) PubChem (68311425) PubChem (68311398) PubChem (143173313) PubChem (177156123) PubChem (5997) PubChem (1551269) PubChem (90070115) PubChem (49853509) PubChem (50990013) PubChem (117965027) PubChem (6432564) PubChem (6710666) PubChem (124146240) PubChem (52934537) PubChem (7059399) PubChem (124897607) PubChem (124896959) PubChem (10861996) PubChem (56621683) PubChem (132837164) PubChem (11834483) PubChem (11888915) PubChem (11888914) PubChem (138967089) PubChem (139566851) PubChem (15939944) PubChem (57915018) PubChem (57939063) PubChem (58428240) PubChem (58445498) PubChem (58663286) PubChem (171828367) PubChem (173516975) PubChem (59450329) PubChem (59628412) PubChem (59965215) PubChem (71234641) PubChem (59993755) PubChem (60001463) PubChem (66634651) PubChem (68055877) PubChem (68166463) PubChem (68315613) PubChem (70795838) PubChem (70797612) PubChem (70954610) PubChem (70957185) PubChem (71463909) PubChem (89951918) PubChem (90224410) PubChem (91298236) PubChem (101624109) PubChem (304) PubChem (124225449) PubChem (191463) PubChem (368063) PubChem (369319) PubChem (124429284) PubChem (638019) PubChem (124909223) PubChem (124909224) PubChem (124909225) PubChem (1549081) PubChem (1553803) PubChem (5283629) PubChem (5284644) PubChem (5315842) PubChem (6419195) PubChem (6994560) PubChem (7055705) PubChem (7055706) PubChem (7059398) PubChem (7059400) PubChem (7059635) PubChem (7103033) PubChem (7182477) PubChem (7182478) PubChem (9909206) PubChem (10045721) PubChem (71168115) PubChem (10134774) PubChem (10293553) PubChem (71173031) PubChem (11003580) PubChem (11025495) PubChem (11058155) PubChem (11463329) PubChem (11868624) PubChem (11868625) PubChem (11869366) PubChem (11869367) PubChem (11869368) PubChem (11869369) PubChem (130459183) PubChem (12120344) PubChem (12156156) PubChem (12303135) PubChem (12303148) PubChem (12303156) PubChem (12303159) PubChem (12303160) PubChem (131992107) PubChem (139568882) PubChem (142983773) PubChem (144054483) PubChem (144209461) PubChem (144331236) PubChem (144808354) PubChem (145053568) PubChem (145157652) PubChem (145215073) PubChem (145230478) PubChem (146320991) PubChem (147857230) PubChem (154993519) PubChem (158603858) PubChem (162906452) PubChem (162906453) PubChem (162906454) PubChem (162906455) PubChem (162906456) PubChem (162906457) PubChem (163255768) PubChem (163389210) PubChem (164665303) PubChem (166553771) PubChem (166712004) PubChem (170116175) PubChem (171764280) PubChem (171817101) PubChem (171817104) PubChem (174285573) | |||
| 7 | J (A) | PALMITIC ACID | non-polymer | 256.4 | 1 | Chemie (PLM) | |||
| 8 | K (A) | DODECAETHYLENE GLYCOL | non-polymer | 546.6 | 1 | Chemie (12P) PubChem (81248) | |||
| 9 | L, M, N, O, P... (A) | SULFATE ION | non-polymer | 96.1 | 6 | Chemie (SO4) | |||
| 10 | R (A) | water | water | 18.0 | 53 | Chemie (HOH) |
Sequence modifications
A: 1 - 230 (UniProt: P07550)
A: 1002 - 1161 (UniProt: P00720)
A: 263 - 365 (UniProt: P07550)
| PDB | External Database | Details |
|---|---|---|
| Asp -6 | - | expression tag |
| Tyr -5 | - | expression tag |
| Lys -4 | - | expression tag |
| Asp -3 | - | expression tag |
| Asp -2 | - | expression tag |
| Asp -1 | - | expression tag |
| Ala 0 | - | expression tag |
| Arg 16 | Gly 16 | conflict |
| Gln 27 | Glu 27 | conflict |
| Glu 187 | Asn 187 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Gly 1012 | Arg 12 | conflict |
| Thr 1054 | Cys 54 | engineered mutation |
| Ala 1097 | Cys 97 | engineered mutation |
| Arg 1137 | Ile 137 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 56601.4 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 342.3 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 3077.1 | |
| All* | Total formula weight | 60020.8 |
