5D4K

Crystal structure of the human polymeric Ig receptor (pIgR) ectodomain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Polymeric immunoglobulin receptor	polymer	557	61483.0	2	UniProt (P01833) Pfam (PF07686) In PDB	Homo sapiens (Human)	Poly-Ig receptor,Hepatocellular carcinoma-associated protein TB6
2	C, D	alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		367.3	2	In PDB GlyTouCan (G86851RC)
3	A, B	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	6	Chemie (NAG)
4	A, B	SULFATE ION	non-polymer		96.1	4	Chemie (SO4)
5		water	water		18.0	58	Chemie (HOH)

Sequence modifications

A, B: 1 - 547 (UniProt: P01833)

PDB	External Database	Details
Ser 347	Gly 365	variant
Gly 548	-	expression tag
Ser 549	-	expression tag
Trp 550	-	expression tag
Ser 551	-	expression tag
His 552	-	expression tag
Pro 553	-	expression tag
Gln 554	-	expression tag
Phe 555	-	expression tag
Glu 556	-	expression tag
Lys 557	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	122966.0
Branched	Number of molecules	2
	Total formula weight	734.7
Non-Polymers*	Number of molecules	10
	Total formula weight	1711.5
All*	Total formula weight	125412.2

*Water molecules are not included.