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5D4K

Crystal structure of the human polymeric Ig receptor (pIgR) ectodomain

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Polymeric immunoglobulin receptorpolymer55761483.02UniProt (P01833)
Pfam (PF07686)
Homo sapiens (Human)Poly-Ig receptor,Hepatocellular carcinoma-associated protein TB6
2C, D
(C, D)
alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched367.32In PDB
GlyTouCan (G86851RC)
3E, F, G, J, K...
(A, B)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.26Chemie (NAG)
4H, I, M, N
(A, B)
SULFATE IONnon-polymer96.14Chemie (SO4)
5O, P
(A, B)
waterwater18.058Chemie (HOH)
Sequence modifications
A, B: 1 - 547 (UniProt: P01833)
PDBExternal DatabaseDetails
Ser 347Gly 365variant
Gly 548-expression tag
Ser 549-expression tag
Trp 550-expression tag
Ser 551-expression tag
His 552-expression tag
Pro 553-expression tag
Gln 554-expression tag
Phe 555-expression tag
Glu 556-expression tag
Lys 557-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight122966.0
BranchedNumber of molecules2
Total formula weight734.7
Non-Polymers*Number of molecules10
Total formula weight1711.5
All*Total formula weight125412.2
*Water molecules are not included.

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PDB entries from 2026-01-14

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