5D2M

Complex between human SUMO2-RANGAP1, UBC9 and ZNF451

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D	SUMO-conjugating enzyme UBC9	polymer	161	18341.1	2	UniProt (P63279) Pfam (PF00179) In PDB	Homo sapiens (Human)	SUMO-protein ligase,Ubiquitin carrier protein 9,Ubiquitin carrier protein I,Ubiquitin-conjugating enzyme E2 I,Ubiquitin-protein ligase I,p18
2	B, E	Small ubiquitin-related modifier 2	polymer	83	9476.6	2	UniProt (P61956) Pfam (PF11976) In PDB	Homo sapiens (Human)	SUMO-2,HSMT3,SMT3 homolog 2,SUMO-3,Sentrin-2,Ubiquitin-like protein SMT3B,Smt3B
3	C, F	Ran GTPase-activating protein 1	polymer	171	18573.5	2	UniProt (P46060) Pfam (PF07834) In PDB	Homo sapiens (Human)	RanGAP1
4	G	Zinc finger protein 451	polymer	65	6907.2	1	UniProt (Q9Y4E5) In PDB	Homo sapiens (Human)	Coactivator for steroid receptors
5	A, C, F	1,2-ETHANEDIOL	non-polymer		62.1	5	Chemie (EDO)
6		water	water		18.0	702	Chemie (HOH)

Sequence modifications

A, D: 1 - 158 (UniProt: P63279)

PDB	External Database	Details
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag
Arg 14	Lys 14	engineered mutation

B, E: 15 - 93 (UniProt: P61956)

PDB	External Database	Details
Gly 11	-	expression tag
Ser 12	-	expression tag
His 13	-	expression tag
Met 14	-	expression tag

C, F: 418 - 587 (UniProt: P46060)

PDB	External Database	Details
Ser 417	-	expression tag

G: 2 - 56 (UniProt: Q9Y4E5)

PDB	External Database	Details
Gly -8	-	expression tag
Ala -7	-	expression tag
Met -6	-	expression tag
Asp -5	-	expression tag
His -4	-	expression tag
Val -3	-	expression tag
Glu -2	-	expression tag
Phe -1	-	expression tag
Gly 0	-	expression tag
Ser 1	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	7
	Total formula weight	99689.6
Non-Polymers*	Number of molecules	5
	Total formula weight	310.3
All*	Total formula weight	99999.9

*Water molecules are not included.