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5D2D

Crystal structure of human 14-3-3 zeta in complex with CFTR R-domain peptide pS753-pS768

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
14-3-3 protein zeta/deltapolymer23026316.82UniProt (P63104)
Pfam (PF00244)
Homo sapiens (Human)Protein kinase C inhibitor protein 1,KCIP-1
2C
(C)
Cystic fibrosis transmembrane conductance regulatorpolymer283256.71UniProt (P13569)Homo sapiensCFTR,ATP-binding cassette sub-family C member 7,Channel conductance-controlling ATPase,cAMP-dependent chloride channel
3D, E
(D, E)
beta-D-fructofuranose-(2-1)-alpha-D-glucopyranosebranched342.32In PDB
BIRD (PRD_900003)
sucrose
4F, G, H, I
(A, B)
CHLORIDE IONnon-polymer35.54Chemie (CL)
5J, K, L
(A, B, C)
waterwater18.0196Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight55890.2
BranchedNumber of molecules2
Total formula weight684.6
Non-Polymers*Number of molecules4
Total formula weight141.8
All*Total formula weight56716.6
*Water molecules are not included.

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PDB entries from 2025-06-18

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