5CZF

Crystal structure of the PaaA2-ParE2 antitoxin-toxin complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	PaaA2	polymer	52	6243.1	2	UniProt (A0A0F6F6Q9) Pfam (PF21217) UniProt (by SIFTS) (Q8XAD5)	Escherichia coli O157
2	C, D (C, D)	Plasmid stabilization protein ParE	polymer	111	12713.4	2	UniProt (A0A0D7C2L1) Pfam (PF05016) UniProt (by SIFTS) (A0A0H3JHG3)	Escherichia coli O157	Plasmid stabilization system protein
3	E, F (C, D)	SULFATE ION	non-polymer		96.1	2	Chemie (SO4)
4	G, H, I, J (A, B, C, D)	water	water		18.0	98	Chemie (HOH)

Sequence modifications

A, B: 13 - 63 (UniProt: A0A0F6F6Q9)

PDB	External Database	Details
Met 12	-	initiating methionine

C, D: 2 - 92 (UniProt: A0A0D7C2L1)

PDB	External Database	Details
Met -18	-	initiating methionine
Gly -17	-	expression tag
Ser -16	-	expression tag
Ser -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
His -9	-	expression tag
Ser -8	-	expression tag
Ser -7	-	expression tag
Gly -6	-	expression tag
Leu -5	-	expression tag
Val -4	-	expression tag
Pro -3	-	expression tag
Arg -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag
His 1	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	37912.9
Non-Polymers*	Number of molecules	2
	Total formula weight	192.1
All*	Total formula weight	38105.0

*Water molecules are not included.