5CXF
Crystal structure of the extracellular domain of glycoprotein B from Human Cytomegalovirus
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Envelope glycoprotein B | polymer | 630 | 72340.2 | 3 | UniProt (P06473) Pfam (PF17416) Pfam (PF17417) Pfam (PF00606) | Human cytomegalovirus (HHV-5) | gB |
| 2 | D (D) | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G81315DD) | |||
| 3 | E (E) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G15407YE) | |||
| 4 | F, G, H, J, K (F, G, H, J, K) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 5 | In PDB GlyTouCan (G42666HT) | |||
| 5 | I (I) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 1 | In PDB GlyTouCan (G22768VO) | |||
| 6 | AA, BA, L, M, N... (C, A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 16 | Chemie (NAG) | |||
| 7 | S (A) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 8 | CA, DA (A, C) | water | water | 18.0 | 2 | Chemie (HOH) |
Sequence modifications
A, B, C: 78 - 706 (UniProt: P06473)
| PDB | External Database | Details |
|---|---|---|
| Gly 155 | Tyr 155 | engineered mutation |
| His 156 | Ile 156 | engineered mutation |
| Arg 157 | Tyr 157 | engineered mutation |
| His 206 | Tyr 206 | engineered mutation |
| Ala 240 | Trp 240 | engineered mutation |
| Thr 241 | Leu 241 | engineered mutation |
| His 242 | Tyr 242 | engineered mutation |
| Asp 434 | - | engineered mutation |
| Asp 434 | Arg 456 | engineered mutation |
| Asp 434 | Thr 457 | engineered mutation |
| Asp 434 | Arg 458 | engineered mutation |
| Lys 434 | Arg 459 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 217020.5 | |
| Branched | Number of molecules | 8 |
| Total formula weight | 4368.1 | |
| Non-Polymers* | Number of molecules | 17 |
| Total formula weight | 3579.4 | |
| All* | Total formula weight | 224967.9 |
