5CSZ

CRYSTAL STRUCTURE OF GANTENERUMAB FAB FRAGMENT IN COMPLEX WITH ABETA 1-11

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (H, A)	GANTENERUMAB FAB FRAGMENT HEAVY CHAIN	polymer	228	24206.1	2		Homo sapiens (Human)
2	B, D (L, B)	GANTENERUMAB FAB FRAGMENT LIGHT CHAIN	polymer	215	23360.0	2		Homo sapiens (Human)
3	E, F (D, E)	Amyloid beta A4 protein	polymer	11	1327.3	2	UniProt (P05067)	Homo sapiens	ABPP,APPI,APP,Alzheimer disease amyloid protein,Cerebral vascular amyloid peptide,CVAP,PreA4,Protease nexin-II,PN-II
4	G, H (H, A)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)
5	I, J (D, E)	SULFATE ION	non-polymer		96.1	2	Chemie (SO4)
6	K, L, M, N, O... (H, L, A, B, D...)	water	water		18.0	742	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	97786.9
Non-Polymers*	Number of molecules	4
	Total formula weight	634.5
All*	Total formula weight	98421.4

*Water molecules are not included.