5CRV
Crystal structure of the Bro domain of HD-PTP in a complex with the core region of STAM2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Tyrosine-protein phosphatase non-receptor type 23 | polymer | 361 | 40584.8 | 2 | UniProt (Q9H3S7) Pfam (PF03097) | Homo sapiens (Human) | His domain-containing protein tyrosine phosphatase,HD-PTP,Protein tyrosine phosphatase TD14,PTP-TD14 |
| 2 | C, D (C, D) | Signal transducing adapter molecule 2 | polymer | 21 | 2370.8 | 2 | UniProt (O75886) | Homo sapiens | STAM-2,Hrs-binding protein |
| 3 | E (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 4 | F, G, H, I (A, B, C, D) | water | water | 18.0 | 365 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 361 (UniProt: Q9H3S7)
| PDB | External Database | Details |
|---|---|---|
| Ala 33 | Asn 33 | engineered mutation |
| Ala 34 | Tyr 34 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 85911.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 92.1 | |
| All* | Total formula weight | 86003.3 |
