5CQA
Crystal structure of the bromodomain of bromodomain adjacent to zinc finger domain protein 2B (BAZ2B) in complex with N-methyl-2,3-dihydrothieno[3,4-b][1,4]dioxine-5-carboxamide (SGC - Diamond I04-1 fragment screening)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Bromodomain adjacent to zinc finger domain protein 2B | polymer | 115 | 13432.4 | 1 | UniProt (Q9UIF8) Pfam (PF00439) In PDB | Homo sapiens (Human) | hWALp4 |
| 2 | A | N-methyl-2,3-dihydrothieno[3,4-b][1,4]dioxine-5-carboxamide | non-polymer | 199.2 | 1 | Chemie (2LY) | |||
| 3 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 4 | water | water | 18.0 | 166 | Chemie (HOH) |
Sequence modifications
A: 1858 - 1970 (UniProt: Q9UIF8)
| PDB | External Database | Details |
|---|---|---|
| Ser 1856 | - | expression tag |
| Met 1857 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 13432.4 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 261.3 | |
| All* | Total formula weight | 13693.7 |
