5CQA
Crystal structure of the bromodomain of bromodomain adjacent to zinc finger domain protein 2B (BAZ2B) in complex with N-methyl-2,3-dihydrothieno[3,4-b][1,4]dioxine-5-carboxamide (SGC - Diamond I04-1 fragment screening)
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue 2LY A 2001 |
| Chain | Residue |
| A | PRO1888 |
| A | PHE1889 |
| A | ASN1944 |
| A | HOH2111 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 2002 |
| Chain | Residue |
| A | MET1875 |
| A | GLU1879 |
| A | THR1968 |
| A | HOH2112 |
| A | HOH2159 |
Functional Information from PROSITE/UniProt
| site_id | PS00633 |
| Number of Residues | 58 |
| Details | BROMODOMAIN_1 Bromodomain signature. AwpFllpvNlklvp..GYKkvIkkpMdfstIreklssgq..Ypnletfaldvrl.VfdNCetF |
| Chain | Residue | Details |
| A | ALA1886-PHE1943 |
