5CQ5
Crystal structure of the bromodomain of bromodomain adjacent to zinc finger domain protein 2B (BAZ2B) in complex with 2,3-Ethylenedioxybenzoic Acid (SGC - Diamond I04-1 fragment screening)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Bromodomain adjacent to zinc finger domain protein 2B | polymer | 120 | 14057.1 | 1 | UniProt (Q9UIF8) Pfam (PF00439) | Homo sapiens (Human) | hWALp4 |
| 2 | B, C (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 3 | D, E (A) | 2,3-dihydro-1,4-benzodioxine-5-carboxylic acid | non-polymer | 180.2 | 2 | Chemie (53E) | |||
| 4 | F (A) | water | water | 18.0 | 177 | Chemie (HOH) |
Sequence modifications
A: 1858 - 1972 (UniProt: Q9UIF8)
| PDB | External Database | Details |
|---|---|---|
| Tyr 1853 | - | expression tag |
| Phe 1854 | - | expression tag |
| Gln 1855 | - | expression tag |
| Ser 1856 | - | expression tag |
| Met 1857 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 14057.1 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 484.5 | |
| All* | Total formula weight | 14541.6 |
