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5CQ5

Crystal structure of the bromodomain of bromodomain adjacent to zinc finger domain protein 2B (BAZ2B) in complex with 2,3-Ethylenedioxybenzoic Acid (SGC - Diamond I04-1 fragment screening)

Functional Information from PDB Data
site_idAC1
Number of Residues5
Detailsbinding site for residue EDO A 2001
ChainResidue
AMET1875
AGLU1879
ALYS1964
ATHR1968
AHOH2103

site_idAC2
Number of Residues3
Detailsbinding site for residue EDO A 2002
ChainResidue
AASN1944
AHOH2102
AHOH2140

site_idAC3
Number of Residues6
Detailsbinding site for residue 53E A 2003
ChainResidue
ALYS1903
ALYS1906
AGLU1945
AASP1946
AHOH2168
ALYS1902

site_idAC4
Number of Residues5
Detailsbinding site for residue 53E A 2004
ChainResidue
ALEU1926
AGLU1927
AARG1934
ATRP1965
APHE1969

Functional Information from PROSITE/UniProt
site_idPS00633
Number of Residues58
DetailsBROMODOMAIN_1 Bromodomain signature. AwpFllpvNlklvp..GYKkvIkkpMdfstIreklssgq..Ypnletfaldvrl.VfdNCetF
ChainResidueDetails
AALA1886-PHE1943

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsMOD_RES: Phosphothreonine => ECO:0007744|PubMed:21406692
ChainResidueDetails
ALEU1918

site_idSWS_FT_FI2
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:21406692
ChainResidueDetails
ATYR1923

226707

PDB entries from 2024-10-30

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